Gut microbita analysis

GA-map® Dysbiosis Test

The world's first and only CE IVD-marked test, designed to diagnose, characterize, and assess the degree of gut dysbiosis.

Tilda Publishing
Gut microbita
analysis
GA-map® Dysbiosis Test
The world's first and only
CE IVD-marked test, designed to
diagnose, characterize, and assess
the degree of gut dysbiosis.
The gut microbiota
Microbiota - is a collective term, which denotes all the intestinal microorganisms, which play an important role in digestion, immunity, etc.
The factors that influence the microbiota are very diverse: genetics, age, diet, physical activity, psycho-emotional state, medications, infections and inflammatory processes.

Modern approaches to regulating microbiota for clinical benefit include: probiotics and prebiotics, combinations thereof (symbiotics), certain antibiotics, lifestyle changes, FODMAP diet, fecal microbiota transplant (FMT
Gut dysbiosis
Dysbiosis - is a permanent or temporary imbalance between different types of natural gut microbiota, associated with IBD and IBS, obesity, nonalcoholic steatohepatitis, diabetes, depression, carcinogenesis, etc.
Clinical studies have shown that 16% of healthy people have moderate dysbiosis (DI 3); in patients with IBD and IBS in 20-30% - normobiosis (DI 1-2), and in 70-80% - severe dysbiosis (DI 4-5).

DI – dysbiosis index
IBD – inflammatory bowel disease
IBS – irritable bowel syndrome

One test, many answers

ONLINE BOOKING
For laboratory testing for gut microbiota
ONLINE BOOKING
For laboratory testing for gut microbiota

GA-map® Dysbiosis Test

Unique opportunities


- A reliable and easy-to-use diagnostic tool for profiling the gut microbiota, that delivers accurate and reproducible results.


- Differentiation of normo- and dysbiotic intestinal microflora in adult patients aged between 18 and 70 years.


- Assessment of the degree of dysbiosis (dysbiosis index) - deviations from the control values of a healthy population.


- Semi-quantitative determination of bacterial 16S rRNA in patient feces.


- A reliable, standardized tool for monitoring changes in the gut microbiota during treatment, lifestyle adjustments, and diets.


- Possibility to create profiles of the human gut microbiota and associate them with patients’ health.

Areas of application

Gastroenterology
Development of new drugs
Nutritiology
Applicable clinical research

Clinical application

Inflammatory
Bowel
Disease
Help in diagnosing, identifying and characterizing gut dysbiosis, treatment monitoring, predicting the treatment effectiveness of patients with ulcerative colitis with inhibitors of tumor necrosis factor (anti-TNF).

Note
The microbiota of patients with a positive therapeutic response differs distinctly from that of patients with a negative response (compared to pre-treatment data). During therapeutic efficacy, the microbiota normalizes much faster than decreases the level of fecal calprotectin.
Irritable
Bowel
Syndrome
Help in diagnosing, identifying and characterizing gut dysbiosis, treatment monitoring, predicting the treatment effectiveness of patients on the FODMAP diet.

Note
FODMAP - "fermentable oligo-, di-, monosaccharides and polyols". These are the so-called simple, poorly digestible carbohydrates that cause the fermentation processes in the gut:
- Food rich in fructans and galactooligosaccharides (wheat, barley and rye, onions and some legumes).
- Food that contains lactose, and fructose with glucose excess (apples, pears, asparagus, watermelon and honey).
- Food rich in mannitol, maltitol, sorbitol and xylitol (peaches, apricots and artificially sweetened foods).
ONLINE BOOKING
For laboratory testing for gut microbiota
ONLINE BOOKING

For laboratory testing for gut microbiota

How it works

Where to take the test in Moldova
GA-map® Dysbiosis Test
is only available from ALFA diagnostica medical laboratory. You collect the biomaterial and send it to the lab.

How to collect material

for analysis

The procedure for collecting feces is described in the instructions that come

with the kit. After collection is complete, the kit should be delivered to any ALFA diagnostica collection center.

Where the test is performed
In the laboratory of Genetic Analysis AS (Oslo, Norway).

Report

You can get it in any center ALFA diagnostica personally, through your legal representative (by power of attorney) or by e-mail.
Validation and standardization for clinical use
GA-map® Dysbiosis Test
Clinically validated and standardized in healthy volunteers and patients with IBD and IBS from across northern and southern Europe.
- Used in more than 50 clinical studies
- Published in 30 peer-reviewed scientific journals
Laboratory report
Laboratory report includes the results of the study: dysbiosis index (ID); functional imbalance - characteristics and ratios in the detected bacterial profiles with comments, prevalence (abundance) of bacteria. The report also contains additional information about the characteristics of individual gut bacterial species.
GA-map® – gut microbiota profiling platform
The innovative technology platform GA-map® uses variable regions (V3 - V9) in the 16S rRNA gene, which is common to all intestinal bacteria.

Molecular targets of bacteria are identified by multiplex analysis using single nucleotide primer extension technology (SNuPE).

For DNA hybridization, 48 molecular probes were used, identifying and characterizing more than 300 species of intestinal bacteria of different taxonomic levels.

The GA-map ™ Dysbiosis Analyzer software automatically compares detected bacterial levels in a patient, with those found in a healthy population, thus reliably differentiating normo- and dysbiotic gut microflora for clinically relevant results.
Price
6000 MDL

Term
14 working days

Код
GEN35

Biological material
Feces

Preparation
1 month before the test, exclude the use of metformin and/or proton pump inhibitors.

How to collect material for analysis
The procedure for collecting feces is described in the instructions that come with the kit.After collection is complete, the kit should be delivered to any ALFA diagnostica collection center.
GA-map® Dysbiosis Test is only available from ALFA diagnostica medical laboratory.
Report
You can get it in any center ALFA diagnostica personally, through your legal representative (by power of attorney) or by e-mail.

Where the GA-map® Dysbiosis Test is performed
In the laboratory of Genetic Analysis AS (Oslo, Norway).

Publication

Contacts

ALFA diagnostica – official partner of Genetic Analysis AS in the Republic of Moldova.

”GENETIC ANALYSIS” AS
About company:
Research and development diagnostic company, a pioneer in the study and mapping of the human microbiome.
The company, the first in the world to develop, document and clinically validate the GA-map® Dysbiosis Test, is designed to diagnose, characterize and evaluate the degree of gut dysbiosis.
Kabelgata 8
0580 Oslo, Norway
+47 48 32 16 10
genetic-analysis.com
”ALFA diagnostica” SRL
About company:
Private medical company, specialized in laboratory clinical diagnosis, international scientific and clinical studies of phases I and II of promising and innovative drug compounds.
Clinical base of the State University of Medicine and Pharmacy "Nicolae Testemitanu" for the training of resident doctors in the field of laboratory medicine
N. Testemitanu street, 21
Chisinau, Republic of Moldova
+373 (22) 82 44 44
alfalab.md
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